All of a sudden, you get tons of warnings like this one:
Warning: setlocale(): Passing locale category name as string is deprecated.
Use the LC_* -constants instead.
in /home/chris/public_html/nuke/mainfile.php on line 565
The problem comes suddenly after your ISP has upgraded to a newer version of PHP (without telling you, of course!
You may get this error again and again. You will have to do the above change in *all* occurences of the LC_something constants! I once counted 17 of them, scattered all around the PHP-Nuke files...